The Potential of Stem Cell Therapy in Treating Neurodegenerative Diseases: Challenges and Future Prospects

Abstract

Neurodegenerative diseases (NDs) such as Parkinson's disease (PD), Alzheimer's disease

(AD), and Huntington's disease (HD) represent a growing global health challenge due to their

progressive nature and lack of effective treatments. In recent years, stem cell therapy has

emerged as a promising treatment modality, offering potential for cellular regeneration,

neuroprotection, and functional recovery. This paper explores the potential of stem cell

therapy in the context of neurodegenerative diseases, identifying key mechanisms,

therapeutic strategies, challenges, and future prospects. Despite promising preclinical and

early clinical studies, significant hurdles such as immunogenicity, ethical concerns, and

regulatory issues remain. This paper concludes with a discussion on ongoing advancements,

the need for more robust clinical trials, and the hope for stem cell-based therapies to reshape

the future of neurodegenerative disease treatment.