Gut Dysbiosis and Its Role in Irritable Bowel Syndrome (IBS): Mechanisms and Therapeutic Approaches

Authors

Gut dysbiosis, Irritable bowel syndrome, Microbiota, Probiotics, Therapeutic approaches, Fecal microbiota transplantation

Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder characterized by

abdominal pain, bloating, and altered bowel movements. Recent research has highlighted the

significant role of gut dysbiosis—the imbalance of the gut microbiota—in the

pathophysiology of IBS. This paper explores the mechanisms by which gut dysbiosis

contributes to the development and exacerbation of IBS, examining the interaction between

the gut microbiota, host immune system, and gastrointestinal function. Furthermore, it

reviews current and emerging therapeutic strategies aimed at restoring microbial balance in

the gut, such as probiotics, prebiotics, dietary interventions, and fecal microbiota

transplantation (FMT). Understanding the interplay between gut microbiota and IBS could

lead to more targeted and effective treatments for this prevalent and often debilitating

condition.