Non-Alcoholic Fatty Liver Disease (NAFLD): Emerging Therapies and Clinical Management

Abstract

Non-Alcoholic Fatty Liver Disease (NAFLD) is a growing public health concern

characterized by the accumulation of fat in the liver in the absence of significant alcohol

consumption. As one of the most common liver disorders worldwide, NAFLD can lead to

severe complications, including cirrhosis and hepatocellular carcinoma. This paper explores

the pathophysiology, risk factors, diagnostic approaches, emerging therapies, and clinical

management strategies for NAFLD. The review highlights the importance of early diagnosis

and the shift toward personalized medicine in managing NAFLD. Novel therapeutic

approaches, including pharmacological treatments targeting metabolic pathways and liver

inflammation, as well as lifestyle interventions, are discussed. This paper underscores the

need for a comprehensive, multidisciplinary approach to managing NAFLD to reduce its

burden on global health.