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Articles

Vol. 1 No. 1 (2025): Vol. 1, No. 1, Year 2025

Hypertension and Its Link to Cognitive Decline: A Review of Mechanisms and Management Strategies

Submitted
April 12, 2025
Published
2025-04-12

Abstract

Hypertension, a prevalent cardiovascular condition, is increasingly recognized for its

significant impact on cognitive health, with numerous studies linking it to cognitive decline

and dementia. This review aims to explore the mechanisms by which hypertension

contributes to cognitive impairment and examine the available management strategies for

mitigating this risk. Both direct and indirect pathways, such as vascular damage,

neuroinflammation, and endothelial dysfunction, are discussed as central to the development

of cognitive deficits. Additionally, pharmacological and non-pharmacological interventions,

including antihypertensive therapy and lifestyle modifications, are critically evaluated in

terms of their effectiveness in preventing or slowing cognitive decline. The review concludes

with recommendations for future research directions to enhance understanding and treatment

options.

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